Patient Resources for Living With Hereditary Angioedema (HAE)

Educational information about HAE, CINRYZE® (C1 esterase inhibitor [human]), and patient support services is available to download below.
For additional support and information, visit ryzeabove.com.

CINRYZE (C1 esterase inhibitor [human]) Prequalification Form

CINRYZE® (C1 esterase inhibitor [human]) Prequalification Form

To get started on CINRYZE, you'll first need to complete this form. The information you provide will help determine whether you may qualify for coverage, decide what your out-of-pocket costs may be, and assess the likelihood that you qualify for financial assistance with any associated costs. Please note that your insurance company may require additional documentation.

Download the English version ›

Download the Spanish version ›

HAE Family Tree Facebook App

HAE Family Tree Facebook App

Build your HAE Family Tree via the interactive app on Facebook. Creating a tree and sharing it with others fosters awareness and encourages your family members to get tested, too.

Create your family tree now ›

HAE Family Health Tree Worksheet

HAE Family Health Tree Worksheet

Track your family history of HAE with the HAE Family Health Tree Worksheet. You can input your data on the interactive version, or you can download and print a PDF to share with your doctor and family members.

Download the English version ›

Download the Spanish version ›

HAE Doctor Discussion Guide

HAE Doctor Discussion Guide

The Doctor Discussion Guide is designed to encourage discussion between you and your doctor about HAE symptoms and the tests needed to confirm a diagnosis.

Download the guide ›

CINRYZEConnect Program Handout

CINRYZEConnect Program Handout

Find out how the CINRYZEConnect program can help you connect with other HAE patients. Once enrolled, you will be matched with a mentor who is receiving therapy with CINRYZE® (C1 esterase inhibitor [human]) and who wants to help others by answering questions and sharing their personal experiences. Click here to learn more and sign up for a mentor.

Download the handout ›

Digital Awareness Kit

Digital Awareness Kit

Share the Hereditary Angioedema Awareness Kit—a variety of helpful resources designed to help you communicate information about HAE and the importance of diagnosis and management.

Access the kit ›

Hereditary Angioedema and You PDF

Hereditary Angioedema and You

This pamphlet created for you and your loved ones explains what HAE is, symptoms and common triggers, and the benefits of a preventive approach.

Download the English Version ›

Download the Spanish Version ›

HAE and Women

HAE and Women

This helpful brochure focuses on the important information that centers around living as a woman with HAE—and about the unique challenges that are specific to women with this condition. Learn how hormones influence HAE and gain an understanding of the impact HAE can have on a woman’s social life, education and even career opportunities.

Download now ›

CINRYZE Patient Brochure PDF

Patient Brochure

This patient brochure gives an overview of CINRYZE® (C1 esterase inhibitor [human]) and contains information on how it works to help prevent HAE attacks, how CINRYZE is made, and what to expect from therapy.

Download the English version ›

Download the Spanish version ›

CINRYZE Solutions Brochure PDF

CINRYZESolutions® Brochure

Learn how the Patient Service Center (PSC) and its Patient Care Coordinators can help your CINRYZE® (C1 esterase inhibitor [human]) therapy go smoothly by finding information on working with your insurance company, locating financial assistance, coordinating delivery of CINRYZE, and more.

Download the English version ›

Download the Spanish version ›

Path to Independence Brochure PDF

Path to Independence Brochure

This brochure explains the details of complimentary resources available to you through the CINRYZESolutions Programs— administration training for eligible patients who are starting self-administration with CINRYZE® (C1 esterase inhibitor [human]), and ongoing education and support for eligible patients who are receiving therapy with CINRYZE.

Download now ›

Self-Administration Instructions Brochure

Self-Administration Instructions Brochure

This brochure provides step-by-step illustrated instructions on how to self-administer CINRYZE® (C1 esterase inhibitor [human]) therapy. After your healthcare provider has taught you how to self-administer CINRYZE, this guide offers additional support.

Download the English version ›

Download the Spanish version ›

Do not attempt to self-administer unless you have been taught how by your healthcare provider.

Connect With an HAE Mentor

Join the CINRYZEConnect™ Program to connect with a mentor who's also living with HAE.

Find out more ›

Looking for Support?

Get financial assistance and insurance guidance from the Patient Service Center (PSC),
the CINRYZESolutions® patient access network.

Find out more ›

Indication
CINRYZE® (C1 esterase inhibitor [human]) is an injectable medicine that is used to help prevent swelling and/or painful attacks in teenagers and adults with Hereditary Angioedema (HAE).

Important Risk Information
You should not use CINRYZE if you have had life-threatening immediate hypersensitivity reactions, including anaphylaxis to the product.

Tell your healthcare provider about all of your medical conditions, including if you:

  • have an indwelling catheter/access device in one of your veins.
  • have a history of blood clots, heart disease, or stroke.
  • are taking birth control pills or androgens.
  • are pregnant or planning to become pregnant. It is not known if CINRYZE can harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if CINRYZE passes into your milk and if it can harm your baby.

Tell your healthcare provider and pharmacist about all of the medicines you take, including all prescription and non-prescription medicines such as over-the-counter medicines, supplements, or herbal remedies.

Allergic reactions may occur with CINRYZE. Call your healthcare provider or get emergency support services right away if you have any of the following symptoms:

  • wheezing
  • difficulty breathing
  • chest tightness
  • turning blue (look at lips and gums)
  • fast heartbeat
  • swelling of the face
  • faintness
  • rash
  • hives

Because CINRYZE is made from human blood, it may carry a risk of transmitting infectious agents, e.g., viruses and, theoretically, the Creutzfeldt-Jakob disease (CJD) agent.

The most common side effects seen with CINRYZE were headache, nausea, rash, and vomiting. These are not all the possible side effects of CINRYZE. Tell your healthcare provider about any side effect that bothers you or that does not go away. You can also report side effects to ViroPharma Medical Information at (866) 331-5637 or the FDA at 1-800-FDA-1088.

Medicines are sometimes prescribed for purposes other than those listed here. Do not use CINRYZE for a condition for which it is not prescribed. Do not share CINRYZE with other people, even if they have the same symptoms that you have.

Before starting CINRYZE, please read the accompanying Patient Information carefully and each time you get a refill. This information does not take the place of talking with your healthcare provider, and it does not include all of the important information about CINRYZE. If you have questions after reading this, ask your healthcare provider.

Please see the Full Prescribing Information.

Was this content
 useful to you?



88% of users have found
  this content useful