Understanding HAE

Scott, a real HAE patient,
helps prevent his
attacks with CINRYZE

Causes of HAE

Most people with hereditary angioedema (HAE) don't have enough of a protein called C1 esterase inhibitor (C1-INH), or the protein their bodies produce does not work the way it should.

When it's at normal levels and working properly, C1-INH helps block overproduction of another protein called bradykinin, which can cause fluid in the blood vessels to leak into surrounding tissue and cause swelling.

HAE is a genetic disease

HAE is called "hereditary" because it is mainly passed down through family members. A person who has a parent with HAE has a 50% chance of inheriting the condition. Still, some people with HAE have no known family history of the disease. HAE can affect anyone and touches men and women of all races.

Passed down from parent

No family history

CINRYZE is the first C1 esterase inhibitor approved to help prevent HAE attacks in children
(6 years of age and older), teenagers and adults.

Learn more about CINRYZE

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