Dariela, a real HAE patient,
helps prevent her
attacks with CINRYZE
If one parent has HAE, the child has a 50% chance of inheriting HAE.
The child could inherit one of four possible C1 esterase gene outcomes at conception.
Since the gene responsible for HAE is a dominant gene, the child only needs one mutated gene from one parent to inherit the HAE condition.
Therefore, if one parent has HAE, the child has a 50% chance of inheriting HAE and a 50% chance of not inheriting HAE.
If the child does inherit HAE, his or her children will also have a 50% chance of inheriting the condition.
If the child does not inherit HAE, he or she will not have HAE or pass on HAE to his or her own children.
It's important to remember that, although HAE is considered a genetic disorder, 25% of HAE patients do not have any family history of the disease because the mutation is new.
CINRYZE is the first C1 esterase inhibitor
approved to help prevent HAE attacks in children
(6 years of age and older), teenagers and adults.
Learn more about CINRYZE